Needing a victory to advance from the group stage after starting their campaign with successive draws, England failed to make their superiority count and were doomed once Trezeguet curled Egypt in front 11 minutes from time.
Flier: Harry Kane gets to the ball ahead of Egypt player Trezeget
Sandwich: Luke Williams finds himself in the middle of Mahmoud Metwaly (left) and Yasser Elhanafi
Match facts
Egypt U20: Awad, El Hanafi, Rabia (Wahid 72), Metwaly, Ibrahim, Kahraba (Rafat 46), Gomaa (Ghaly 62), Mohamed, Hamad, Trezeguet, Koka. Subs Not Used: Hamdi, El Hadad, El Hambaly, Bassam, El Shami, Sherif, Mahmoud.
Booked: Ghaly, Trezeguet.
Goals: Trezeguet 79, Koka 90.
England U20: Johnstone, Dier, Stones, Thorpe, Garbutt, Coady, Ward-Prowse (Reach 62), Cole (Chris Long 74), Barkley, Kane, Williams (Pritchard 46). Subs Not Used: George Long, Bigirimana, Flanagan, Lascelles, Lundstram, Ripley.
Ref: Antonio Arias (Paraguay).
Booked: Ghaly, Trezeguet.
Goals: Trezeguet 79, Koka 90.
England U20: Johnstone, Dier, Stones, Thorpe, Garbutt, Coady, Ward-Prowse (Reach 62), Cole (Chris Long 74), Barkley, Kane, Williams (Pritchard 46). Subs Not Used: George Long, Bigirimana, Flanagan, Lascelles, Lundstram, Ripley.
Ref: Antonio Arias (Paraguay).
But Hassan Ahmed's stoppage-time effort piled further humilation onto an England outfit that slumped to the bottom of Group E as Iraq and Chile advanced.
England have now gone 16 matches without a win at this level and a summer that promised so much will instead trigger another bout of navel-gazing.
Taylor acknowledged tonight's display was the worst of his reign, and rued the missed opportunities.
'I thought we would win tonight, to be honest, because I thought we were improving as a team,' he said.
'Unfortunately, it was our worst performance since we've been here, but I don't think I've seen a team create as many chances and lost a game 2-0 and that's why it's frustrating.'
He continued: 'If you don't play as well as you can and you don't take chances, you get punished, and that's what happened tonight.
'Egypt showed good character to win the match tonight having lost the previous two games.
'We still feel we could have scored more goals and that's the mistake that we made.
'Their first goal was very well taken and the second came when we were trying to get back into it.'
Taylor tried to look for positives following his team's exit, adding: 'The experience of playing in the U20 World Cup will have been fantastic for everybody.
'It's a brilliant competition, but we're disappointed.'
Tricky: Larnell Cole attempts to get away from two Egyptian defenders
Eyes on the ball: Tom Thorpe watches as Hassan Ahmed wins a header
Ghana went through to the first knockout round as the 16th and last team because of a better goal difference than Iraq and will play Portugal.
Uruguay defeated Uzbekistan 4-0 to secure a place in the knockout stages on Saturday.
Gino Acevedo scored with a low 25-metre shot in the 38th minute, and Nicolas Lopez, Giorgian de Arrascaeta and Ruben Bentancourt added in the second half.
Uruguay finished Group F second to Croatia, and will take on Nigeria in the play-offs. Uzbekistan also advanced as one of the best third-placed teams and will meet Greece.
Croatia, already qualified, beat New Zealand 2-1 with goals from Stipe Perica and Ante Rebic. Louis Fenton scored New Zealand's only goal in the tournament from the penalty spot in the 84th.
The U20 World Cup continues on Tuesday with the first four matches of the knockout stage, including tournament favorites Spain against Mexico.
Fifty-fifty: Larnell Cole and Rabia Ramy challenge for the ball
Close call: England's Thomas Thorpe climbs above the defence but puts his header wide
Delight: Trezeget (left) celebrates his wonderful strike
Lost cause: England's head coach Peter Taylor tries to rally the troops
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